SELECTIVE SPECTROPHOTOMETRIC DETERMINATION OF LEVODOPA

Selective extraction spectrophotometric determination

Selective spectrophotometric determination of diltiazem hydrochloride in tablets.

Diltiazem hydrochloride (Ia) is an important coronary vasodilator drug of the calcium channel-blocker type, used in therapy of heart disease and hypertension. The compound is (+)-5-[2-(dimethylamino)ethyl]-c&, 2,3dihydro3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate monohydrochloride. The drug and its tablet formulations are official in the USP [l] wherein they are estimated...

Selective Cloud Point Extraction for the Spectrophotometric Determination of Cetylpyridinium Chloride in Pharmaceutical Formulations

In this work, we developed a simple and selective method for separation and spectrophotometric determination of trace amounts of cetylpyridinium chloride (CPC) in pharmaceutical products using cloud point extraction (CPE) technique. The method is based on cloud point extraction of the CPC in alkali conditions using of nonionic surfactant Triton X-114. Under selected conditions, the calibration ...

Selective Cloud Point Extraction for the Spectrophotometric Determination of Cetylpyridinium Chloride in Pharmaceutical Formulations

In this work, we developed a simple and selective method for separation and spectrophotometric determination of trace amounts of cetylpyridinium chloride (CPC) in pharmaceutical products using cloud point extraction (CPE) technique. The method is based on cloud point extraction of the CPC in alkali conditions using of nonionic surfactant Triton X-114. Under selected conditions, the calibration ...

Selective Spectrophotometric Determination of Metformin Hydrochloride in Pharmaceuticals and Urine Using Two Nitrophenols as Chromogenic Agents

      Metformin hydrochloride (MFH) is an oral anti-diabetic drug of biguanide class. Two selective spectrophotometric methods were presented for the determination of MFH in pharmaceuticals. The methods were based on the measurement of yellow-coloured charge-transfer complexes formed between MFH and two poly-nitrophenols, namely, 2,4-dinitrophenol (DNP method, at 405 nm) and picric acid (PA met...